Tongkat Ali is generally well-tolerated in human studies at the doses used here — but a specific safety review is worth understanding in its proper context.
A 2021 EFSA review flagged DNA damage concerns from a high-dose animal study using far larger amounts, relative to body weight, than this formula's human dose.
High-dose animal studies using amounts far exceeding a human supplement dose are a genuinely different risk category from the doses used in human research — if you have specific concerns, discuss them with your doctor before use rather than dismissing or overstating the finding.
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